IL17A and colorectal carcinoma: Interestingly, a multivariate Cox’s regression analysis revealed that age (hazard ratio = 1.98, p = 0.04), site of lesion (hazard ratio = 3.14, p = 0.02), overall stage (hazard ratio = 1.37, p = 0.03), CCL20 (hazard ratio = 1.12, p = 0.001), IL-17A levels (hazard ratio = 1.22, p = 0.04) and the combination of CCL20 and IL-17A (hazard ratio = 1.45, p = 0.04) were independent prognostic factors for the OS of CRC patients (Additional file 1: Table S4).