In general, biomarker tests have less than perfect sensitivity (true positive probability), mainly because the progression of the load (concentration) of a disease-related biomarker (e.g., the HIV viral RNA, measured by the NAT) in the infected host follows various phases post-exposure, with varying growth rates, e.g., pre ramp-up phase, ramp-up phase with accelerating growth rates, and post ramp-up phase, with the biomarker load tending to a plateau or significantly diminishing due to a resolved infection (e.g., [10, 20]). Here, BRD2 is linked to infection.