PMAIP1 and cervical carcinoma: Treatment of cervical cancer cells with RAME induced transcription of apoptosis-related genes (Bax, Noxa, and Puma) and DNA repair gene (Gadd45α), whereas the mRNA levels of the cell cycle arrest genes (p21 and 14–3-3α) were not altered by RAME treatment (Fig. 5d, e).