CXCL8 and dry eye syndrome: Furthermore, IL-36 procytokines directly induce expression of Th17 cytokines, proinflammatory cytokines and chemokines TNF-α, IL-6, IL-8, CCL17, CCL22 and CXCL8 in KCs [16,105] and increase IL-17A-mediated induction of antibacterial peptides [51].