HMOX1 and metabolic dysfunction-associated steatohepatitis: The aim of this study is to investigate the role of HO in two of the main processes involved in the NASH pathology, using the human hepatocellular carcinoma cell line (HepG2) treated with free fatty acids (FFA), and the human hepatic stellate cells (LX2) treated with TGF-β, as steatosis and fibrosis models, respectively.