According to one study [94], some K-ras mutant NSCLC cell lines, including A549, H23, and SK-LU-1, were not K-ras-dependent cells and do not require K-ras to maintain viability, and inhibiting or knocking down K-ras does not suppress the proliferation, migration, and invasion abilities in these cells. Here, KRAS is linked to non-small cell lung carcinoma.