According to the Spearman rank correlation analysis, in all CHD patients, including STEMI and SAP patients, plasma NGAL was positively correlated with MMP-9 (r = 0.601, P<0.001) (Fig 1A) and IL-1β (r = 0.159, P = 0.014) (Fig 1B); however, there was no statistically significant correlation between NGAL and hs-CRP (r = 0.026, P = 0.684) (Fig 1C). This evidence concerns the gene IL1B and coronary artery disorder.