Within our cohort of 27 patients who had undergone ECAS testing during life, we identified a subgroup of six patients that demonstrated no cognitive impairment when assessed by the ECAS, but did exhibit extra‐motor TDP‐43 pathology when assessed at post mortem, so called mismatch cases, and 11 patients who had TDP‐43 and corresponding cognitive dysfunction; one with executive dysfunction, two with fluency dysfunction, six with language dysfunction and two with a mixed cognitive deficit (Table 1). Here, TARDBP is linked to Cognitive impairment.