This revealed a statistically significant increase in expression of neuronal clusterin in mismatch cases (P < 0.001, two‐way ANOVA with Bonferroni correction for multiple comparisons) and a statistically significant increase in expression of glial clusterin in cases with TDP‐43 pathology with a cognitive deficit (P < 0.001, two‐way ANOVA with Bonferroni correction for multiple comparisons; Figure 2A,B). The gene discussed is CLU; the disease is Cognitive impairment.