The results shown in Fig 6 suggest that the dissolving-microneedle-patch loaded OVA induced an OVA-specific CTL response that targeted the EG7 tumor cells through the cytolytic activity of the responding T cells, and this process was tested directly by measuring the OVA-expressing EG7 target cells using the LDH-release assay and the induction of OVA-expressing EG7-specific IFN-γ-producing CD8+ cells. The gene discussed is CD8A; the disease is neoplasm.