We infected Ifnar1-/- and WT C57Bl6 littermate controls intranasally with 5 × 107 CFU of either P. aeruginosa and S. aureus. Mice were sacrificed at 2- and 6 hr post-infection and bronchoalveolar lavage (BAL) was performed for quantification of cytokine production and neutrophil recruitment. Here, IFNAR1 is linked to infection.