Quizartinib treatment in previous phase 2 trials demonstrated composite complete remission (CRc) rates of 44–47% in patients with relapsed or refractory FLT3–ITD-mutated AML, and 34–42% of patients were bridged to potentially curative hematopoietic stem cell transplant [5–7]. This evidence concerns the gene FLT3 and acute myeloid leukemia.