Lowest IC50 values were shown by BPA and BPE (144.3 ± 3.2 μg/ml and 180.5 ± 3.6 μg/ml) respectively followed by BPB (255.0 ± 2.2 μg/ml), BPM (345.6 ± 2.1 μg/ml) while the highest IC50 was observed for BPH and BPC (618.3 ± 4.0 μg/ml and 764.8 ± 2.5 μg/ml) respectively. The gene discussed is DST; the disease is benign prostatic hyperplasia.