Differences in the level and physical contact of sCXCR4-A with cancer cells could directly affect tumor growth through induction of apoptosis after binding to CXCR4-expressing ID8-T cells, followed by phagocytosis of tumor cell debris by DCs (Figures S2A and S2B), a process required for induction of antitumor immune responses.8 Here, CXCR4 is linked to cancer.