CXCR4 and ovarian carcinoma: We first assessed the effect of intravenous (i.v.)or intraperitoneal (i.p.)delivery of soluble and virally delivered CXCR4-A, expressed in-frame with the murine Fc fragment of immunoglobulin G2a (IgG2a; OVV-CXCR4-A), in C57BL/6 mice challenged i.p. with a highly metastatic syngeneic ovarian cancer cell line (ID8-T).