CD8A and neoplasm: Because intratumoral infiltration of CD103+ DCs is one of the major requirements for establishing a T cell-inflamed tumor phenotype because of production of CXCL9 and CXCL10 chemokines, which promote recruitment of effector CXCR3+ CD8+ T cells,37 we next examined whether this mechanism could also be used to increase survival and bolster tumor-specific T cell responses following virotherapy.