These plants have traditionally been indicated for treatment of obesity and hyperglycemia.36 Studies have described possible molecular mechanisms underlying the hypoglycemic effect of APCs or plant extracts containing these compounds,47, 48, 49, 50, 51, 52 but none of these studies revealed the SGLT1 inhibiting activity. This evidence concerns the gene SLC5A1 and obesity due to melanocortin 4 receptor deficiency.