CASP3 and chronic myelogenous leukemia, BCR-ABL1 positive: Furthermore, a prior study found thatMjTX-I, a PLA2 from Bothrops moojeni, is able todiminish cell viability of chronic myeloid leukemia cells (K562-S and K562-RBCR-ABL+) and induce apoptosis through activation of Caspases 3, 8and 9 [20].