GAD1 and latent autoimmune diabetes in adults: As shown in the Supplementary Fig. S2, hsa-miR-517b-3p expression shows significant negative correlation with GAD antibody titer (Pearson correlation = −0.684, P = 0.014), in line with its observed down-regulation in LADA patients in both microarray (Table 2) and qRT-PCR (Fig. 5) assay.