GEM and neoplasm: Prospectively, as shown in Fig. 4a, sequencing results indicated that many proliferation and migration-associated tumor suppressor genes (e.g., GCNT3, FBP1, XDH, GEM, SLIT3, TNFATP3, et al.)or oncogenes (e.g., ALPP, ALPPL2, MMP13, MUC1, MYB, CD7, et al.)were differentially up- or down-expressed, respectively, subsequent to DANCR knockdown.