Different types of immunomodulatory agents, such as immunoglobulin (IgG), IgM-enriched immunoglobulin (IgGAM), granulocyte-colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF) and human antibodies to endotoxin (antilipopolysaccharide), have been evaluated for use in treating neonatal sepsis. This evidence concerns the gene CSF2 and Neonatal sepsis.