EBF3 and melanoma: Evaluation of EBF3 CpG sites (at chr10:131636622–131671489, GRCh37; cg03774288, cg07890827, cg09121772, cg09371530, cg09649486, cg16803064 and cg25866634), in a cohort of 450k data of melanocytes (n = 3), primary melanomas (n = 4) and melanoma metastases (n = 33 in total) (Fig. 1b, left), showed that the EBF3 gene body was hypomethylated (~ 40% loss of methylation on average) in melanoma metastases (green and magenta boxplots) compared to primary melanomas (red boxplots) or melanocytes (blue boxplots).