Given the detection of the highest expression levels of TALAM1 in the triple negative breast cancer cell line MDA-MB-231 (Fig. 1a) as well as in epithelial breast cells exposed to TGF-β (Fig. 1b), we next enquired about the biological role of this natural antisense transcript (NAT) in the functional properties of breast cancer cells. The gene discussed is TALAM1; the disease is breast carcinoma.