Interestingly, SFRP1 levels in AH samples from patients with POAG (1.98 ± 0.12 ng/ml) (P = 0.54), CACG (1.71 ± 0.13 ng/ml) (P = 0.34), PACS (1.84 ± 0.18 ng/ml) (P = 0.85) and AACG (1.97 ± 0.10 ng/ml) (P = 0.53) were not significantly different from that of controls (Fig. 1b). The gene discussed is SFRP1; the disease is open-angle glaucoma.