Although ATM (mutation rate: 2.4%), BRCA1 (0–1%), BRCA2 (8–19%), CHEK2 (2.9%), and PALB2 (3.1–3.7%) have been identified as the genes responsible for HPC, known germline mutations account for less than 20% of all cases of HPC [18]. The gene discussed is BRCA2; the disease is hereditary chronic pancreatitis.