Interestingly, this study also showed that in a multivariate analysis model including age, serum levels of albumin, hs-CRP, the Charlson Comorbidity index score, education level, and history of smoking, severe periodontitis was an independent risk factor for all-cause mortality (hazard ratio = 1.83, 95% CI; 1.04–3.24, p < 0.05), but not cardiovascular-related diseases (hazard ratio = 1.95, 95% CI; 0.90–4.23, p = 0.09) [11]. Here, CRP is linked to periodontitis.