DVL1 and myocardial infarction: For example, a mouse model of myocardial infarction showed the dysregulation of expression of WNT2, -4, -7b, -10b and -11 as well as FZD1, -2, -5, -8 and -10 [186,187,188,189], and mice mutants for Dvl1 are more susceptible to infarct rupture after induction of myocardial infarction [178].