RIGI and infection: Additionally, Odendall et al. have shown that, in the context of infection with Listeria monocytogenes (a bacteria that is signaled by the RIG-I/MAVS pathway and induces mitochondrial disruption [51,52]), peroxisomal MAVS has a dominant role in the coordination of an IFN response, since the expression of peroxisomal MAVS strongly potentiates the production of type I and type III IFNs in Jeg3 trophoblasts [34].