Among the patients with RA there were some correlations between the different biomarkers at T0 and markers of disease activity in RA or traditional CVD risk factors; MPO with DAS28 (r = -0.4, p = 0.001), sCD40L with CRP (r = 0.3, p<0.01) and IL-18 with systolic blood pressure (r = 0.3, p<0.05) as well as with Reynolds risk score (r = 0.4, p<0.05). This evidence concerns the gene MPO and rheumatoid arthritis.