In this case, local healthcare units would need to coordinate active call of patients, risk assessments, genetic counseling, preventive or treatment pathways, cascade screening etc. A BRCA1/2 genetic test could also be delivered in a specialist care setting, such as an oncology clinic, where women with breast cancer may be advised to take the test on the basis of their personal and family history. The gene discussed is BRCA1; the disease is breast carcinoma.