We hypothesized that (1) there will be no difference in AA‐, ADP‐, and COL‐induced MEPA between dogs with AKI and healthy dogs; (2) there will be no difference in vWF:Ag, vWF collagen binding activity (vWF:CBA), and vWF:Ag to vWF:CBA ratio (vWF:Ag:vWF:CBA) between dogs with AKI and healthy dogs; and (3) there will be strong correlation between BMBT and these primary hemostatic variables measured. This evidence concerns the gene RENBP and acute kidney injury.