The intensity of IRF4 binding to IL-10 DNA of CD4+CD25hiFoxp3+Treg cells in patients with ITP was higher than that of normal control group (1.16 ± 0.06 vs 0.29 ± 0.03, p=0.0051) Figure 3(c). This evidence concerns the gene CD4 and autoimmune thrombocytopenic purpura.