CDKN2A and coronary artery disorder: This locus contains several genes including CDKN2A (encoding cyclin p14, p16), CDKN2B (encoding cyclin p15), MTAP (encoding methylthioadenosine phosphorylase), and the long non-coding RNA ANRIL. Integration of genetic and transcriptomic data led to the identification of ANRIL as the top candidate causal gene for CAD at the 9p21 region (63).