In CP-CML, DNMT3A, EZH2, RUNX1, and TET2 were found to be mutated (Schmidt et al., 2014), whilst in a separate study, BP-specific SNVs were found in TET2, ASXL1, and IDH1 (Makishima et al., 2011). The gene discussed is EZH2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.