MMP7 and cancer: MT-MMP (Rozanov et al., 2004), MMP3 (Yamashita et al., 2011), MMP9, and matrilysin (MMP7) (McGuire et al., 2003) localize to adherens junctions to shed the E-cadherin ectodomain, producing a soluble fragment frequently increased in the serum of cancer patients (Repetto et al., 2014).