When cells were treated with BAFF and sub-toxic concentrations of drugs used in conventional ALL treatment, like aracytine or the glucocorticoids dexamethasone, prednisolone, hydrocortisone, methylprednisolone, the addition of BAFF significantly enhanced glucocorticoid-dependent apoptosis of 697 cells (Figures 4B,C), but not of Jurkat cells. Here, TNFSF13B is linked to acute lymphoblastic leukemia.