CACNA1C and major depressive disorder: Recent genomic investigations and analyses have suggested that autoantibodies and receptors, such as calcium voltage-gated channel subunit alpha 1C (CACNA1C) and calcium voltage-gated channel auxiliary subunit beta 2 (CACNB2), are among the primary risk factors for psychotic disorders, major depressive disorder (MDD), autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and obsessive-compulsive disorder (OCD) [57].