TP53 and breast cancer: Meanwhile, P53 translocation to the nucleus and the activation of caspase-3 were significantly increased (Figures 7(b) and 7(d); ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001), suggesting the antiapoptotic property of HSPA9 in the breast cancer cells.