The colocalization of HSPA9 and P53 was detected in the perinuclear region in many types of cancer cells, such as HeLa (cervical carcinoma, wt P53), U2OS (osteosarcoma, wt P53), A172 (glioblastoma, wt P53), NT-2 (teratocarcinoma, wt P53), SY-5Y and YKG-1 (neuroblastoma, wt P53), MCF7 (breast carcinoma), and human adenocarcinoma cell lines [32]. The gene discussed is TP53; the disease is osteosarcoma.