BRCA1 and breast cancer: Currently, there is little evidence to support an association between germline mutations in STK11 and TNBC as mutations in STK11 were not observed in (1) a cohort of 2,134 BRCA1/BRCA2 mutation negative women with familial breast cancer, (2) 1,824 women of primarily white ethnicity with TNBC [39, 41], and (3) 4,797 women of mixed ethnicities with TNBC [40].