Sun et al. (2018) have reported a hypermethylation of CD36, correlated with low expression in primary lung tumors. CD36 inhibited migration, invasion, and proliferation of lung cancer cells and arrested cell cycles in G0/G1 phase. Furthermore, treatment with decitabine, an inhibitor of DNA methylation and chidamide, an HDAC inhibitor, decreased the methylation and increased the mRNA expression level of CD36. This evidence concerns the gene CD36 and lung carcinoma.