GPI and arthritic joint disease: In two models of arthritis in mice, antigen-induced arthritis (AIA), a mouse model of human rheumatoid arthritis, and glucose-6-phosphate isomerase-induced arthritis, a severe form of polyarthritis, GRdim mice were, respectively, fully or partly resistant to intravenous Micromethason (liposomal encapsulated DEX) treatment (122).