In relation to the CD8+ T cells subsets, we found that patients in PD tended to have a higher porcentage of CD8+ TEMRA cells (median [range]: PD vs. HD, 48.3 [13–67] vs. 29.9 [17–72]) and a lower frequency of TCM cells than patients in HD (median [range]: HD vs. PD, 16.3 [6.2–31] vs. 7.8 [3.1–27]), but the magnitude of the difference was not sufficiently great to be statistically significant in the small sample of patients analyzed. Here, CD8A is linked to Huntington disease.