Sixty-four patients had a Del 22q11.2 defect (DiGeorge syndrome), 63 had an ataxia telangiectasia mutated gene (ATM) (A-T), 36 had a STAT3 mutation (Hyper IgE syndromes), 24 had a WASP mutation [Wiskott-Aldrich syndrome (WAS)]. The gene discussed is STAT3; the disease is Wiskott-Aldrich syndrome.