Moreover, P. copri has been associated to enhancing susceptibility to inflammatory disorders like arthritis through intrinsic Th17 promoting capability, driving cytokines IL-6 and IL-23 (Scher et al., 2013) and has been associated to systemic inflammation status too (Creely et al., 2007; Pedersen et al., 2016). This evidence concerns the gene IL6 and Arthritis.