This suggests that although IL-6 and INF-α contribute into MS pathogenesis, data on level of eight cytokines (IL-1β, IL-2, IL-4, IL-8, IL-10, IL-13, IFN-γ, and TNF-α) in serum provides sufficient input data to diagnose and classify MS. Here, CXCL8 is linked to myeloid sarcoma.