Our bioinformatic analysis predicted that there was another candidate target of miR-200a-3p, PRKACB, a universally conserved gene that encodes one of the paralogous catalytic subunits of PKA that increases the levels of phosphorylated tau at Ser214, Ser356, and Ser396 epitopes by a number of kinases, widely reported in AD brains and mouse models (Wang et al., 2013; Wang et al., 2015). This evidence concerns the gene MAPT and Alzheimer disease.