S100A4 and colorectal carcinoma: Among them, pioneering studies demonstrated that their dysregulation may result in the progression of CRC, such as AZGP1 (Ji et al., 2013; Chang et al., 2014; Xue et al., 2014b), APOBEC3G (Ding et al., 2011; Lan et al., 2014), BST2 (Mukai et al., 2017), TRIM29 (Jiang et al., 2013; Xu et al., 2016), and S100A4 (Dahlmann et al., 2014; Fei, 2017).