Interestingly, scoring of gastric atrophy, intestinal metaplasia, xanthoma and mucus in FD patients with low levels of acylated ghrelin were significantly higher (p<0.001, p = 0.0077, p = 0.036 and p = 0.0063, respectively) compared to those in FD patients with more than low levels of acylated ghrelin (Table 4). This evidence concerns the gene GHRL and Fabry disease.