IL17A and Neonatal sepsis: Of note, IL‐2 is a potent inflammatory mediator disrupting the blood‐brain barrier and altering brain microcirculation that underlies vascular leak syndrome and brain autoimmune inflammation.20 Furthermore, suppression of IL‐17A is particularly significant in microbial and autoimmune inflammation.180 In neonatal sepsis, the recently identified axis comprising IL‐18/IL‐1R1/IL‐17 contributes to mortality.181