Finally, KEGG pathway analysis alsoshowed similar results, in terms of the number of genesinvolved in the adhesion junction, pathways in cancer,MAPK signaling pathway, Wnt signaling pathway, PI3KAKTsignaling pathway, HIF-1 signaling pathway, TGF-beta signaling pathway, as well as the signaling pathwaysregulating pluripotency of stem cells, P53 signalingpathway and cell cycle (Fig .4D). Here, TP53 is linked to cancer.