Actually, simultaneous deregulation of miR200cand miR-30c could significantly reduce the survivalrate of breast invasive carcinoma cells via up-regulationof OCT4, SOX2, c-MYC, SNAI1, ZEB1, CDH2 and down-regulation of CDH1 (P=0.02, Fig .4E). This evidence concerns the gene ZEB1 and invasive breast carcinoma.