Tumor suppressormiR-34a regulates some molecules involved in cellsurvival pathways, and p53/miR-34a regulatory axis mayplay important roles in sensitizing NSCLC cells (28).Through c-Fos/c-Jun pathway, interleukin 7 (IL7) /IL7-Renhance vascular endothelial growth factor-D (VEGF-D)expression and contribute to lymphangiogenesis in lungcancer (29). This evidence concerns the gene TP53 and non-small cell lung carcinoma.