Therefore, 19 studies 17, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39 with 1316 bone and soft tissue sarcoma patients were included in the meta‐analysis, and data from 13 studies were used to evaluate the clinicopathological significance and data from 17 studies were used to evaluate the prognostic value of ezrin expression. The gene discussed is EZR; the disease is soft tissue sarcoma.