MCL1 and small cell lung carcinoma: Consistently, MYC-amplified SCLC cell lines (n = 4) were more sensitive to MCL1 inhibitor S6384526 compared to MYCN- (n = 3) and MYCL- (n = 4) amplified cell lines (p = 0.003 MYC vs. MYCN; p = 0.001 MYC vs. MYCL, two-tailed unpaired t test) (Fig. 3c, d and Supplementary Fig. 3a).